Age-Related Macular Degeneration – Potential Roles for Nutraceuticals in its Prevention and Control

Age-related macular degeneration (AMD) is the leading cause of partial blindness in the elderly. This essay reviews what is known of its origins, emphasizing evidence that oxidative stress is a key mediator of this syndrome, and summarizing evidence that fish oil omega-3 fats, the carotenoids lutein and zeaxanthin, as well as a range of other antioxidants, may have be useful for preventing or slowing it. Suggestive evidence that the B vitamin folic acid, as well as soy isoflavones, may also aid control of AMD is presented.