Dietary Saturate/Unsaturate Ratio as a Determinant of Adiposity

Diets in which the ratio of saturated to unsaturated fats is low – such as “Mediterranean” or most plant-based diets – tend to be associated with good muscle insulin sensitivity and a compensatory reduction of daily insulin secretion. Since insulin acts on the body’s fat cells to promote storage, retention, and synthesis of fat, it is proposed that reduced daily insulin secretion may help to account for the relative leanness of people who are long-term practitioners of vegan or Mediterranean diets low in saturated fat.

Published in Medical Hypotheses 2010;75(1):14-6.

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